RE: [RC] oops....IN strangles vaccine - Susan E. Garlinghouse, DVM
>Sorry, now I am
giving mis-information. I am not sure if the IN strangles vaccine
actually replicates...it is >live,
though.
>Sorry again....got
carried away. Terminology is a powerful thing especially when misused!
The live intranasal virus does replicate, but is modified so
that, in theory, it cannot survive/replicate outside the lower temps of the nasal
mucosa. Thus, again in theory, it will not survive in the higher core
body temperatures to replaicate and cause clinical disease. I cannot say
from my own experience that this never happens, or whether it happens to a statistically
significant degree.
I have never had clinical disease occur in horses that I’ve
vaccinated myself with the intranasal strangles vaccine---several
hundred---which in itself is a statistically insignificant number.
