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[RC] EHV-1 A Must Read On Vaccinating Part 1 of 4 - Don Huston

This was posted on <naturalhorsetrim@xxxxxxxxxxxxxxx> and I thought it contained valuable info that all of us horse people could use.
The ridecamp server rejected the email when sent as one complete document because it's too big so I broke it into 4 parts.
Happy New Year
Don Huston

                          Part 1 of 4

Here is an essay on the subject by a California vet. Noel S. Muller, DVM
Los Caballos Equine Practice, Inc. Please note
especially his third to last paragraph in Part 4 quoted here for emphasis:

In the simplest terms: Do not vaccinate your horse if your horse has
potentially been exposed to EHV1. Treat him like royalty for 21 days and
keep your ears and eyes open to what is happening in your local area. If
he shows no signs of disease at 21 days, go back to your old routine.
Feel free to vaccinate him at that point in time. The most effective
vaccine to use prior to exposure is Rhinomune (Pfizer). Repeat the
vaccination in three weeks.

=======================================================

HERE IS THE FULL TEXT:

There has been a well publicized outbreak of the neurological form of
EHV1 that has occurred in Wellington, Fla. over the past two weeks. This
outbreak has now spread to California. A cargo load of show horses
shipped from New Jersey to LAX on approximately 12/10/06. Included among
the equine passengers was a horse already deeply into the contagious
form of the disease that had vanned up from Wellington. After landing in
LA, this animal shipped to Del Mar. Within 48 hours of his arrival in
Del Mar he began showing a high fever (over 105) and signs of
depression. Despite appropriate treatment, he quickly showed the classic
signs of weakness and ataxia (drunkenness) involving primarily the rear
legs. He became recumbent, was unable to rise and was put down. This all
happened within 72 hours of his arrival in CA (source, Dr. Paul
McClellan, private correspondence, 12/18/06).

The other horses in the same load were unknowingly dispersed to various
points in CA. As of this writing, several are showing fevers and the
barns are under a voluntary quarantine. It remains to be seen whether
these measures will be sufficient to prevent further spread of the
disease. Most probably we will continue to see other small outbreaks.
Please understand that these outbreaks do not feel small if they occur
in or near your barn. The feelings that are generated among the
unfortunate horse owning public in proximity to an outbreak must be akin
to what people worldwide felt in the early part of the twentieth century
as the Great Influenza Plague swept world wide. The outbreak is not
small if you stand any chance of being involved. It is only through
diligence that we will be able to control this outbreak. The earliest
signs of infection are fatigue, depression and fever. Horses with this
and many other diseases act like they have a deep, dull head ache (to
me, if a horse acts like he has a headache, he has a headache). If you
have a horse with these signs, especially if there has been horse
traffic in your barn within the previous 10 days, please call your
veterinarian. I will discuss the public's and the veterinarian's role in
controlling this outbreak toward the end of this essay.

It is interesting to note that the disease is currently not a reportable
disease in California. That means that health authorities are not
required to track the disease, to keep statistics on it or to
disseminate information to health workers. It also means that all
quarantines in this state are strictly voluntary in nature. Horse owners
tend to be a responsible, inquisitive sort and there would be intense
peer pressure against any individual knowingly breaking even a voluntary
quarantine. There may also be legal ramifications if a person willfully
and knowingly breaks quarantine. This would be similar, I think, to AIDS
carriers being sued for spreading the disease by continuing to engage in
unprotected sex.

EHV1 is a herpes viral infection. Like other herpes viruses, it can lie
dormant within the body for weeks, months and even years. While dormant,
it escapes notice of the bodies own immune system until it can begin to
multiply rapidly enough to cause clinical signs. It is able to suddenly
multiply not by undergoing some mutation that allows it to escape
surveillance. Rather, it is via a breakdown in the body's immune
surveillance or response system. In essence, there is a "dip" in the
ability to mount an appropriate immune response. The most common cause
of a decreased immune response is that over worked word, stress. This
can be in the form of poor nutrition, pain, anti-inflammatory drugs used
to decrease pain, travel, changed social structures (think: break up
with a boyfriend and the cold sore that you sometimes get after that; of
course, sometimes a break up is a joyous occasion!) or concurrent
disease states. Vaccinations are a stress on the body sufficient to
cause a transient but significant dip in immunity.

The majority of EHV infections in horses are EHV1 or 4. EHV1 is much
more prevalent and more serious. There are three forms: respiratory,
late term abortions in pregnant mares or, rarely, the neurological form.
EHV4 is strictly respiratory infections. The neurological form is the
most serious and often progresses to recumbency and death. Treatment is
limited to supportive help and some direct anti viral medication.
Survivors are chronic shedders.
                          See Part 2

Don Huston  <donhuston@xxxxxxx>

Don Huston  <donhuston@xxxxxxx>