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RE: [RC] West Nile Virus - Adverse Reaction - Susan E. Garlinghouse, D.V.M.Sorry to hear of your adverse reaction adventure, hope your horse is okay now. I've heard of similar reactions via online veterinary discussion groups. Lots of gray hairs among the vets that had to deal with them. I haven't personally witnessed any such reactions, because we don't use the Merial product in our practice (and your experience illustrates why). The only adverse reaction we've had to the Fort Dodge product is very minor muscle soreness --- less so than is commonly experienced after vaccinating for flu/rhino or the Eastern/Western/tetanus combo. By the way, there was also a recent journal article that demonstrated no increase in broodmare abortions in relationship to vaccination with WNV vaccines, contrary to some of the wild rumours flailing hither and yon the past year or two. We pushed vaccinating the pregnant mares in our practice and haven't had any problems --- coincidentally, the only mare that aborted this year hadn't been vaccinated for anything. Her owner preferred the "natural" method of broodmare management. :-( JME. Hope you've recovered with a few stiff shots of single malt. Susan Garlinghouse, DVM, MS -----Original Message----- From: ridecamp-owner@xxxxxxxxxxxxxxxxx [mailto:ridecamp-owner@xxxxxxxxxxxxxxxxx] On Behalf Of Ridecamp Guest Sent: Saturday, April 09, 2005 10:30 AM To: ridecamp@xxxxxxxxxxxxx Subject: [RC] West Nile Virus - Adverse Reaction Please Reply to: Deborah Anderson seillean@xxxxxxxxxxx or ridecamp@xxxxxxxxxxxxx ========================================== On 4.07.05 my 9 yr old Arabian Gelding was given a 2nd Recombitek (Merial) 6 month booster and experienced a severe anaphylactic-like reaction approximately 40 minutes later. He had his lst Recombitek injection <previous, 5 Ft Dodge boosters, before this new drug was used and recommended by our local DVM> last October and exhibited signs of colic a few hours later. My horse was given Flu/Rhino (sp) @ the same time. He also had his teeth floated. Was given sedative for this procedure. The reaction in October 2004 started out several hours later displaying symptoms of "tying-up" and soon progressed to pawing and trying to get down to roll. Full blown gas colic before vet arrived. DVM administered NAISDS and drugs for gas colic. My gelding was better the next day but stocked up behind. DVM felt that too many vaccines/drugs given @ one time. Fast forward to today. Today, 40 mins after being given the vaccination,<the only booster administered> he was down in the pasture. I walked out to the pasture, his pasture buddy ran to the gate. My horse got up, ran to the gate and began bucking and kicking in place. Pooped. Started pawwing. He got up and down. We did not try and retrain him, obviously in serious pain. DVM called immediately. My best friend who is ER RN was with me. Horse was acting like his entire body hurt. He would stretch out, turn his head toward his left side, point his hind leg toward his nose and bend. This is how an episode began last year. Next get down, rolled a bit, stopped and then stretched out on the ground (similar to horses who have HYPP attacks) head on the ground arced away from his front legs. His respiration/breathing was very fast. It was if he was going into anaphylactic-like shock. The episode would subside he would get up and stand for a bit. Dull eyes. Obviously in pain. These seemed to occur every 11 minutes. Minutes seem like hours when one is waiting for the vet. My gelding got down and was still laying on his chest. Resting, not rolling...we let him stay down and rubbed his large muscles. This seemed to comfort him. We felt very helpless. The vet finally arrived, 40 minutes or more had passed. Got him up, listen to his heart and gut. Administered banamine and another drug for the gas (don't remember the name, began with a "D") Within minutes, the horse was feeling better much to everyone's relief. My DVM was white as a sheet. I probably was too. I am not using this Recombetec vaccine again. I would rather deal with the virus or go back to using the Ft. Dodge product. My DVM has promised to contact Merial and report the incident. I hope to have some feedback in 10 days or so. I asked him to record the lot number etc. of the vaccine. He almost tossed it out in the trash. We would have been dumpster diving! If anyone has experienced similar situation, or if you have any suggestions regarding this adverse reaction, I would truly appreciate it. Thank you for your time. seillean@xxxxxxxxxxx =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=- Ridecamp is a service of Endurance Net, http://www.endurance.net. 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