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Re: [RC] [RC] SCID : Calling vets and breeders - heidi - heidi

Please Reply to: Erick Larson paradigm@xxxxxxxxxxx or
ridecamp@xxxxxxxxxxxxx ==========================================

OK, I'm completely ignorant (my wife agrees!).

What is SCID?  Layman's terms please.

Severe Combined Immune Deficiency.  Clinically, the foals are born unable
to produce either B-lymphocytes or T-lymphocytes.  (There are some other
conditions in which one or the other is lacking...)  The B-lymphocytes are
the ones that produce antibodies, and the T-lymphocytes are the ones that
do cell-mediated immunity.  Consequently, the resulting foals have no
defense against infection, once the maternal antibodies from the colostrum
are gone.

The condition also exists in humans--think "bubble babies" that have to
live in a completely sterile environment to survive...

Heidi



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Replies
Re: [RC] [RC] SCID : Calling vets and breeders - heidi, Ridecamp Guest