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Authors A Berg, M Peters, P Deibert, D Konig, H Birnesser
Title   Bromelain - Overview and diskussion of therapeutic application and its 
importance in sports medicine and sports traumatology
Full source     Deutsche Zeitschrift Fur Sportmedizin, 2005, Vol 56, Iss 1, pp 
12

Bromelain, a plant-derived proteolytic enzyme, is commercially available and 
has been approved as a pharmaceutical preparation. Bromelain is mainly 
prescribed for the treatment and prevention of inflammatory, posttraumatic or 
postoperative swelling. The mode of action has been investigated in 
cell-culture and animal experiments. In controlled clinical studies in humans, 
orally-administered Bromelain has proven its pharmaceutical efficacy by 
significantly reducing soft-tissue edema in the above-mentioned conditions. 
Therefore, Bromelain is also of interest for sports medicine and sports 
traumatology. Oral treatment with Bromelain has few and only transient and mild 
side-effects and may therefore be an effective alternative for non-steroidal 
anti-inflammatory drugs in the treatment of posttraumatic edema and swelling. 
This review summarizes present knowledge regarding the mode of action of 
Bromelain and gives an overview about its practical applications from a 
sports-medical point of view.


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