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Re: [RC] [RC] HYPP-N/H - sindy mccosker



Carolyn, N/H (heterozygous) horses can show physical signs of the disease. I took this off of the AQHA website. They have an excellent resource center for HYPP.

Can symptoms of HYPP vary in severity?

Clinical signs of HYPP do vary widely among different horses. Homozygous horses are affected more severely than heterozygous horses. Under ideal management practices, the defective gene does not appear to have adverse effects, but stress and/or increased potassium in the serum can trigger clinical signs of muscle dysfunction. Why some horses manifest severe signs of the disease and others exhibit little or no signs is unknown, but currently under investigation. Unfortunately, a horse carrying the defective gene, but showing minimal signs, has the same chance of passing the gene to future generations as does the affected horse with severe signs.


Sindy McCosker Newcastle, CA (The Gem of the Foothills)

"Some horses come into our lives and guickly go. Others stay a while, make hoofprints on our hearts and we are never, never the same."
-anonymous-






From: "Carolyn Burgess" <carolyn_burgess@xxxxxxxxxxx>
To: Jon.Linderman@xxxxxxxxxxxxxxxxx
CC: ridecamp@xxxxxxxxxxxxx
Subject: [RC]   HYPP-N/H
Date: Mon, 13 Jan 2003 12:27:46 -0500

Horses that are HYPP-N/H will have no problems in terms of physical issues related to HYPP. However, they are carriers and if breed to another HYPP-N/H horse, will have a 1 in 4 chance of producing a horse with HYPP, a 1 in 2 chance of producing a N/H horse and a 1 in 4 chance of producing a N/N horse. If breed to a N/N horse they will still have a 1 in 2 chance of producing a N/H horse, or another carrier.

Carolyn Burgess



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