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[RC] West Nile treatment FYI. - Laurie Durgin

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From:   Melissa Chappell <macdwc@xxxx>
Date:  Fri May 30, 2003  8:07 am
Subject:  Treating WNV with Plasma - TX horses




Plasma - Part I: Living proof in Texas that horses can beat the West Nile Virus

By Katie Tims



These Percheron mares are the donors that supply Alpha Equine
with 250 liters of plasma per year. They are universal
donors, meaning their plasma can be used in horses with any
blood type, and they are vaccinated every two weeks for 15
diseases. Courtesy of Quarter Horse News
Thirty-nine horses. That's how many cases of verified West
Nile Virus infections were treated with plasma at the Alpha
Equine Hospital in Weatherford, Texas. That's how many cases
Dr. M.C. Baker and his staff veterinarians, Dr. Britt Conklin
and Dr. Justin High, cured.

"None of the ones we treated did we have to put to sleep,"
Baker plainly stated. "Some of them were so far along that
they had to be pulled out of the trailer on their sides."


About two days, that was the average time it took for those horses to stop exhibiting the shaking and paralysis that accompanied onset of the West Nile Virus. The pregnant mare stayed about six months to ensure a safe delivery of her foal, but the other 38 horses were each released in less than two weeks' time.

With the first infected horse not diagnosed until October,
Dr. Baker was taken aback by the rapid spread of the disease
into Texas. "I was personally a little skeptical at first,"
he said about the initial horse they suspected might have the
West Nile Virus. "When we sent the blood off and it came back
positive, I was surprised. I mean I was even surprised we had
it here because we don't see many mosquitoes around here."

Last year, 14,717 horses in 40 states were reported to have
had the West Nile Virus. Texas was the hardest hit. According
to USDA statistics compiled from Jan. 1 through Dec. 31,
2002, the state had 1,597 horses come down with the West Nile
Virus. Not a single case was reported in the Lone Star state
just one year before.

Although Dr. Baker did not have a background in treating
horses infected with West Nile Virus, he had years of
experience with horses suffering from a myriad of other
neurological diseases and disorders that exhibited many of
the same symptoms. At the time the first symptomatic horse
was unloaded at his clinic, the relatively new West Nile
Virus did not top Dr. Baker's list of possible diagnoses. Dr.
Conklin immediately sent blood off to be tested and didn't
hesitate to begin treatment. Encephalomyelitis, EPM, ear
infections, moldy corn poisoning, parasites or abscesses in
the brain, Rhino, yellow star thistle poisoning, and such,
the veterinarian considered all the possibilities.

"For a lot of those things you don't wait for the test to
come back to confirm what you treat," Dr. Baker said. "There
are 15 neurological diseases that are acute and they all
exhibit themselves pretty much the same."

The moment the first symptomatic horse arrived, it was given
massive doses of Dexamethasone for up to three days straight,
standard administering of Banamine twice a day, around 400ccs
of DMSO once or twice a day plus a constant drip of IV
fluids. In unison, the medications worked to relieve the
horse's pain, reduce swelling and maintain hydration. They
did not, however, pack the power punch that knocked the virus
off course. That was up to the blood plasma, one liter of
which was infused into the jugular vein. For two more days,
one liter of plasma was infused into the horse's bloodstream.

Was the plasma the reason Alpha Equine had a 100 percent cure
record for horses treated for the West Nile Virus? "Oh yes,
without a doubt," Dr. Baker answered. "With that high of a
success rate, I think you have to give plasma the credit."

Continued Reprinted with permission from Quarter Horse News

~~___(\
_/< >\__________
"To error is human, to forgive, Equine" ~~unknown


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