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Jan Mutchler
A deficiency of B-1, B-6, and magnesium can cause a horse, especially
mares, to exhibit signs of hypersensitivity.  Hypersensitivity should be
differentiated from signs that a "hot horse" would have.  A hypersenstive
horse will be overly sensitive to environmental and tactile stimuli, i.e.
horse hates to be brushed even with the softest of brushes, doesn't like
being petted or stroked, loses focus while eating, tendency towards
diarrhea, and very hard in general to keep the horse focused.  Its kind of
like they have raw nerve endingings and anything you do to them is very
uncomfortable.  I learned that it is best to start with a 500mg
supplementation of B-6.  If you see some positive results from that (i.e.
more comfortable with brushing, less diarrhea), then start adding in the
B-1.  I read that you can supplement up to 1000mg B-1.  You should see
more positive results with the added B-1.  My literature research also
indicated that if you see positive results with the B-6 and B-1, that the
horse may also be deficient in magnesium.  Magnesium deficiency can
manifest itself in two ways: muscle cramping or hypersensitivity.  I do
not know if B-1 would test as a "masking agent" or not.  Although, it
seems to me that since it is a natural substance inherent in the system,
that it shouldn't test positive, but who knows.  Kind of like using
Thyro-L or Regumate.  And, that brings up something else - if you think
your horse is truly hypersensitive - get a complete thyroid panel done.
Thyroid imbalance can also sometimes cause a horse to be hypersensitive.
Me, personally, I wouldn't give my horse high amounts of the B's until I
determined if my horse was truly hypersensitive and it has a thyoid panel
done.  Just my thoughts.
Jan Mutchler

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