DMG again

Lynn E Taylor (LTaylor@otterbein.edu)
Fri, 25 Oct 1996 11:46:35 +0000

OK, 2 more cent's worth...not to be fussy, BUT...until I see
published results in a peer-reviewed journal, I am not convinced of
anything. Numbers of horses, statistics, methodology are all
difficult to assess, and the professional community demands that
academics regulate themselves by reviewing each other's work. Some
points to consider:

1. How do studies come uo with dosages? Has anyone done a toxicity
study on DMG?

2. Blood lactate and plasma lactate are 2 different things. Which is
measured? When was it sampled? What type of anti-coagulant was used?
How was it stored after collection? How long before it was assayed?
Blood lactate is always lower than plasma lactate because the red
cell contents dilute the concentration - there is not an equilibrium
of lactate distribution across the red cell and plasma.

3. What if the timing of DMG feeding is still incorrect? How many
timing regimens were initially tested?

4. Why would endurance horses need lower lactate? The levels during
an endurance ride are fairly low - nothing even close to racing,
polo, cutting, reining, junping, cross-country, etc.

5. What is really going on during recovery? What are horses doing at
this time? Walking? Standing? Turned out? In stalls? Massaged? Fed
differently? All these things can affect recovery varaibles.

6. Are there interactions in studies with training effects? maybe all
groups of horses are fitter.

7. What are the possible detrimental effects of DMG?

So anyway, not to be too uppity, but there are lots of research
projects out there. They need to be carefully planned out, and
subjected to rigorous statistical analysis. If they pass the grade,
great, I will read it and ponder it myself. If it only ends up in a
meeting proceedings book, or The Equine Athlete etc., then I begin to
wonder why it was possibly rejected from a quality journal. Well,
there is my pompous and supicious 2 more cents...PLEASE nobody sned
me hate mail, we all have to be careful about believing everything we
read!!!..Lynn

Lynn E. Taylor, MS, PhD
Assistant Professor
Dept. of Equine Science
Otterbein College
Westerville, Oh 43081

ltaylor@otterbein.edu